Umubare munini wa buffers urakenewe muburyo bwo kwegeranya busukuro bwibinyabuzima butari. Ukuri kandi byoroshye kwihuta bigira ingaruka zikomeye muburyo bwo kwezwa bwa proteine. Gutandukana kumurongo hamwe na sisitemu yo gufata kumurongo birashobora guhuza ibintu bitandukanye bigize impeta. Inzoga za nyina na Dilunt bavanze kumurongo kugirango ubone igisubizo kigenewe. Ibicuruzwa bishingiye kubumenyi bwa siyansi, kandi ubwiza buturuka mu gitekerezo cyo gushushanya (QBD). Binyuze mumwanya nyacyo kumurongo (mugihe nyacyo) Gukurikirana no kugenzura ibipimo bibiri byimiti, ibiranga imiterere (CQA), menya mugihe cyo gukora ibintu bihamye kandi bifatika kugirango bishobore gukora ibigo byabiyemoho. Igikorwa gakondo cyogutegura amazi gisaba umubare munini wibigega nibinini binini. Iven yazanye abakiriya uburambe bushya bwa tekiniki, bigabanya ikirenge cya buffer mu rwego rwo kwezwa, no kugabanya ibiciro byabanjirije hamwe na nyuma yo gukora. , Kunoza imikorere yumusaruro, menya neza ibipimo ngenderwaho (CPP) ya buffer hamwe nubushakashatsi bwayo, hanyuma amaherezo itezimbere imiti.